KEGG   Cricetulus griseus (Chinese hamster): 100762079
Entry
100762079         CDS       T02813                                 
Symbol
Bace1
Name
(RefSeq) beta-secretase 1
  KO
K04521  beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:cge00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100762079 (Bace1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cge01002]
    100762079 (Bace1)
Enzymes [BR:cge01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.46  memapsin 2
     100762079 (Bace1)
Peptidases and inhibitors [BR:cge01002]
 Aspartic peptidases
  Family A1: pepsin family
   100762079 (Bace1)
SSDB
Motif
Pfam: Asp TAXi_C TAXi_N PE-PGRS_C
Other DBs
NCBI-GeneID: 100762079
NCBI-ProteinID: XP_027267840
UniProt: G3IAK4
Position
4:157566683..157593312
AA seq 501 aa
MAPALRWLLLWVGSGMLPAQGTHLGIRLPLRSGPAGPPLGLRLPRETDEESEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHIANVFSLQLCGAGFPLNQTEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq 1506 nt   +upstreamnt  +downstreamnt
atggccccggcattgcgctggctcctgctatgggtgggctcgggaatgctacctgcccag
ggtacacatcttggcatccggctgccccttcgcagcggcccggcagggccacccctgggc
ctgaggctgccccgggagaccgacgaggaatccgaagagcctggccggagaggcagcttt
gtggagatggtggacaacctgaggggcaagtcaggccaaggctactatgtagagatgact
gtaggcagccccccacaaacgctcaacatcctggtggacacgggcagtagtaactttgca
gtgggggctgccccacaccctttcctgcatcgatactaccagaggcagctgtccagcaca
tatcgagacctccgaaagggtgtgtatgtgccctatacccagggcaagtgggagggggag
ctgggcactgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatc
gctgccatcactgagtcggacaagttcttcatcaatggttccaactgggagggcatccta
gggctggcctatgctgagattgccaggcccgatgactccctggagcccttctttgactcg
ctggtgaagcagacccacattgccaatgtcttttccctgcagctctgtggcgctggcttc
cccctcaaccagactgaggcactagcctcagtgggagggagcatgatcattggcggtatt
gaccactcgctatacactggcagtctttggtacacacccatcagacgggagtggtattat
gaagtgatcattgtacgtgtggaaatcaatggtcaagatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagtgggaccaccaatcttcgtttgcctaagaaa
gtgtttgaagctgcagtcaagtccatcaaggcggcctcctcgacggagaagttccccgat
ggcttttggctaggggagcagctggtgtgctggcaagcaggcactaccccttggaacatt
ttcccagtcatctcactttacctcatgggtgaggtcaccaatcagtccttccgcatcacc
attcttcctcagcaatacctacggccggtagaagatgtggccacatcccaagatgactgt
tacaagttcgccatctcacagtcatccacaggcactgttatgggagctgtcatcatggaa
ggcttctatgtggtttttgaccgggcccgaaagcgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacggcggcagtggaaggtccttttgttacaccagacatg
gaagactgtggctacaacattccacagacagatgagtcgacacttatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgttgccactctgcctcatggtatgtcagtgg
cgctgcctacgctgcctgcgccatcagcatgatgactttgctgatgacatctccctgttg
aaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (28)   

Download RDF
DBGET integrated database retrieval system